News       Events

Recognised Research Group (RRG) Awards Portfolio

Recognised Research Groups (RRGs) were an integral part of the HPSS R&D Strategy between 2000-2010 and accounted for a large component of the HPSS R&D Fund expenditure. The RRGs were established in the period between 2000 & 2002 with additional calls for proposals following on in 2003, 2005 & 2007. The concept was intended to facilitate focused good quality research and to create critical mass within vibrant co-operative research environments.

RRG Theme Title Chief Investigator Dates Cost (£)
Epidemiology
The PRIME Study extension
Prof Frank Kee
2002-2006
926,179
Epidemiology
An investigation of periodontal disease as a putative risk factor for coronary heart disease and stroke.
Prof Gerry Linden
2002-2006
325,381
Epidemiology
Genetic and Molecular Investigation of Ischaemic Heart Disease Using Family Based Studies 
Prof Pascal McKeown
2002-2006
563,949
Child Health & Welfare
Nutrition, air pollution and lung disease.
Prof Madeleine Ennis 
2002-2007
417,082
Child Health & Welfare
Pathophysiology of childhood asthma.
Dr Michael Shields 
2002-2007
720,729
Child Health & Welfare
Long term outcome in relation to steroid use after birth in a population of very preterm children randomised to receive early or late systemic or inhaled steroids in the neonatal period.
Prof Henry Halliday
2001-2003
77,102
Child Health & Welfare
Examination of Homeobox gene expression in lung and blood cells of preterm babies.
Prof Henry Halliday
2002-2004
274,037
Child Health & Welfare
Habituation in the normal and abnormal foetus.
Prof Peter Hepper
2004-2009
423,416
Child Health & Welfare
Risk factors and protective mechanisms in Failure to Thrive in young children
Dr Moira Stewart
2003-2005
278,488
Child Health & Welfare
The psychosocial impact of facial discrepancy requiring surgical correction
Dr Donald Burden
2005-2007
141,412
Child Health & Welfare
Attitudes to breastfeeding:  A health educational initiative with adolescents
Dr Melanie Giles
2005-2006
86,278
Child Health & Welfare
Can peer mentoring in first time mothers from socially deprived areas, during pregnancy and the first year of the infant’s life, have sustained effects on child growth, health and development and maternal health and well-being?
Prof Henry Halliday
2007-2009
234,305
Child Health & Welfare
Changing attitudes to breastfeeding:  The evaluation of an evidence based intervention with adolescents in Northern Ireland
Dr Melanie Giles
2007-2010
327,616
Child Health & Welfare
A longitudinal investigation of teasing/bullying among children with cleft lip and/or palate
Dr Donald Burden
2007-2010
357,909
Vision
To evaluate the impact of visual impairment and a variety of rehabilitation strategies on visually impaired adults and children in Northern Ireland.
Prof Jonathan Jackson
2002-2009
407,148
Vision
The study of inherited ophthalmic disorders.
Miss Giuliana Silvestri
2002-2007
483,594
Vision
An investigation of the cellular and molecular mechanisms leading to vascular cell dysfunction during diabetic retinopathy
Prof Alan Stitt
2002-2007
160,223
Vision
Advanced lipoxidation end-products and the pathogenesis of diabetic retinopathy
Dr Tim Curtis
2005-2007
168,298
Vision
Is age-related macular degeneration less common in light-protected populations?
 
Dr Giuliana Silvestri
2007-2010
319,333
Vision
Genetic and phenotypic characterisation of retinal dystrophy patients in NI
Dr David AC Simpson
2007-2011
475,647
Vision
Molecular dissection of sporadic and familial keratoconus in Northern Ireland
Dr Colin E Willoughby
2007-2010
435,168
Diabetes, Endocrinology & Nutrition
Inadequate sperm: a molecular biological investigation of the commonest endocrine disorder.
Prof Sheena Lewis
2001-2004
149,876
Diabetes, Endocrinology & Nutrition
Pathophysiology and clinical relevance of insulin action in hypertension, diabetes and pituitary disease.
Dr Brew Atkinson
2001-2006
544,985
Diabetes, Endocrinology & Nutrition
Diabetes, obesity, intrauterine growth and atherosclerosis: the fetal origins hypotheses.
Dr David R McCance
2001-2009
702,475
Diabetes, Endocrinology & Nutrition
The use of stable long-acting analogues of GIP and GLP-1 for diabetes therapy.
Dr Patrick Harriet
2002-2005
130,530
Diabetes, Endocrinology & Nutrition
Non-invasive determination of vascular impedance properties of the ocular circulation in vivo
Prof Gary McVeigh
2002-2005
281,278
Diabetes, Endocrinology & Nutrition
Developing evidence-based practice in diabetes care
Prof Vivien Coates
2002-2006
110,434
Diabetes, Endocrinology & Nutrition
Vascular complications of diabetes mellitus: cellular pathophysiology.
Prof Elizabeth Trimble
2002-2007
392,856
Diabetes, Endocrinology & Nutrition
Mapping of genetic susceptibility genes for nephropathy and albuminuria employing novel family studies in type 2 diabetes
Dr Christopher Patterson
2002-2007
183,998
Diabetes, Endocrinology & Nutrition
Identification of the Genetic Predisposition to Diabetic Nephropathy.
Prof Peter Maxwell
2003-2007
527,886
Diabetes, Endocrinology & Nutrition
A genome wide search for susceptibility genes for nephropathy and albuminuria employing novel family studies in type 2 diabetes.
Dr Damian Fogarty
2003-2007
309,021
Diabetes, Endocrinology & Nutrition
The genetic basis of hyperlipidaemia and vascular disease in Northern Ireland
Dr Colin Graham
2003-2008
574,563
Diabetes, Endocrinology & Nutrition
Diabetes proteomics, pancreatic beta cell targets and drug discovery.
Prof Peter Flatt
2003-2008
207,288
Diabetes, Endocrinology & Nutrition
Effects of Omega-3 Fatty Acids on Platelet and Vascular reactivity in patients with type 2 diabetes mellitus and hypertension
Prof Dennis Johnston
2004-2007
243,387
Diabetes, Endocrinology & Nutrition
Production and secretion of glycated forms of intestinal GLP-1 and GIP:  Involvement in hormonal control of glucose metabolism and diabetes
Dr Aine Marie McKillop
2005-2007
131,015
Diabetes, Endocrinology & Nutrition
A longitudinal of periodontal disease as a putative risk factor for coronary heart disease and stroke
Prof Gerard Linden
2007-2013
402,244
Diabetes, Endocrinology & Nutrition
Genetic association analyses of functional candidate genes for diabetic nephropathy identified by a genome-wide microsatellite screen
Dr David Savage
2007-2009
213,701
Diabetes, Endocrinology & Nutrition
Pathophysiology of insulin resistance and insulin secretion defects and the development and progression of diabetes:  influence on diet and autoimmunity
Dr Steven J Hunter
2007-2010
504,901
Diabetes, Endocrinology & Nutrition
Doppler ultrasound investigations of ocular and skeletal microcirculations in Type 1 Diabetes Mellitus
Prof Gary McVeigh
2007-2011
459,528
Diabetes, Endocrinology & Nutrition
Studies of the prevalence and determinants of obesity and cardiovascular risk in young children:  The HAPO Family Study
Dr David R McCance
2007-2012
679,151
Diabetes, Endocrinology & Nutrition
An investigation into the modulation of obesity-associated monocyte/macrophage function, vascular inflammation and insulin resistance by PPAR agonist treatment
Dr Lesley Powell
2007-2010
353,931
Diabetes, Endocrinology & Nutrition
Insulin action and vascular risk:  influence of endocrine replacement and antihypertensive therapies
Prof Patrick M Bell
2008-2011
441,669
Cancer
Characterisation of a novel candidate ovarian tumour suppressor gene.
Dr Hilary Russell
2002-2007
453,306
Cancer
Enhancement of anti-tumour efficacy by targeting tumour-specific micro-environmental factors.
Prof David Hirst
2002-2007
205,071
Cancer
Further characterisation of a novel gene, DIR1, and other stress response genes with a potential role in radio and chemosensitivity.
Dr Tracy Robson
2002-2007
217,540
Cancer
Discovery of potential novel anti-cancer drugs derived from natural products and by rational design.
Dr Hendrik van den Berg
2002-2007
222,974
Cancer
Epigenetic gene silencing in cancer.
Dr Colum Walsh
2002-2007
233,814
Cancer
Late cell cycle checkpoints in cancer.
Prof Stephen Downes
2003-2008
239,855
Cancer
Functional analysis of the BRCA1 tumour suppressor gene in response to DNA damage and cytotoxic stress.
Prof Paul Harkin
2001-2006
350,423
Cancer
The pathogenesis and treatment of anaemia in cancer.
Prof Terry Lappin
2002-2005
283,434
Cancer
Characterisation and clinical significance of TS regulated signalling pathways
Prof Patrick Johnston
2001-2006
429,808
Cancer
Evaluation of biological activity of faecal water as biomarker for colon cancer risk
Prof Ian Rowland
2001-2004
118,031
Cancer
Folate status and carcinogenesis
Dr Helene McNulty
2002-2004
116,596
Cancer
The role of machine vision and computerised expert systems in the diagnosis and prognosis of cancer.
Prof Peter Hamilton
2002-2007
130,057
Cancer
Pathways of inflammation associated oncogenesis of the colon
Prof Frederick Campbell
2002-2006
358,885
Cancer
Genetic screening in breast and breast/ovarian cancer families
Dr Anthony Bjourson
2004-2007
192,621
Cancer
The validation and integration of (18FDG) PET-CT functional data into the radiotherapy treatment planning process for non-small cell lung cancer
Dr Alan Robert Hounsell
2005-2008
267,762
Cancer
Oesophageal adenocarcinoma in Barrett’s oesophagus:  contribution of the Northern Ireland Barrett’s Register and mathematical modelling
Dr Brian Johnston
2005-2008
166,304
Cancer
Long term follow-up of middle-aged men with elevated prostatic specific antigen levels:  a population based study
Dr Anna Gavin
2005-2007
201,389
Cancer
The role the insulin growth factor axis and folate metabolism in the oesophageal inflammation, metaplasoa, adenocarcinoma sequence
Dr Liam Murray
2007-2009
219,282
Cancer
Expression profiling of circulating colorectal cancer (CRC) epithelial cells:  Clinical Relevance
Prof Patrick Johnston
2007-2012
905,949
Cancer
To develop and validate a test for the diagnosis and prediction of response to therapy in the BRCA1 deficient/basal sub type of breast cancer
Prof Paul Harkin
2007-2012
941,275
Cancer
Clonal methylation profiling of morphologically normal mucosa as a risk marker of colitis-associated colorectal neoplasia (CACRN)
Prof Frederick Campbell
2007-2011
369,555
Trauma & Rehabilitation
Autologous cultured osteoblasts in the treatment of delayed fracture union
Dr Canice McGivern
2003-2007
571,091
Trauma & Rehabilitation
Cerebral palsy population-based survey
Mr Aidan Cosgrove
2003-2008
478,564
Trauma & Rehabilitation
Arthritis: Joint Destruction Vs Joint Repair
Dr Madeleine Rooney
2003-2009
586,688
Trauma & Rehabilitation
Phenytoin in the treatment of chronic wounds
Mrs Julia Shaw
2004-2008
248,379
Trauma & Rehabilitation
Preferential wound healing in the oral mucosa
Prof Chris Irwin
2003-2005
156,236
Trauma & Rehabilitation
The assessment of imaging performance of X-ray Imaging Systems using both practical and computer modelling approaches applied to clinical situations
Dr Kieran Cranley
2003-2007
220,346
Trauma & Rehabilitation
Real and Virtual 3D Environments
Dr John Winder
2003-2005
130,725
Trauma & Rehabilitation
A comparison of Bobath therapy and gait-specific training in acute stroke:  a randomised controlled trial
Dr Sheila Lennon
2005-2007
83,083
Trauma & Rehabilitation
Treatment of shoulder pain by injection and physiotherapy
Dr Ian Ryans
2008-2012
266,157
Trauma & Rehabilitation
The identification of infection and proteomic biomarkers in the progression of juvenile and adult arthritis
Dr Madeleine Rooney
2007-2010
325,945
Trauma & Rehabilitation
Drug delivery to open wounds using novel semi-solid devices as an augmentative strategy for laceration repair
Dr Mark Jenkins
2007-2011
723,698
Trauma & Rehabilitation
Predicting poor hand functional outcome in Rheumatoid Arthritis – a comparison of high-resolution ultrasound examination and occupational therapy clinical hand assessment
Dr Aubrey Bell
2008-2015
291,008
Trauma & Rehabilitation
Group Exercise Therapy for Mobility and Balance in People with Multiple Sclerosis (MS):  a Randomised Controlled Trial
Dr Andrea Lowe-Strong
2008-2012
428,563
Trauma & Rehabilitation
Exercise and auricular electroacupuncture:  a subject-and assessor-blind feasibility randomised controlled trial of the effectiveness of a combined approach for chronic low back pain
Prof Suzanne McDonough
2007-2009
174,094
Infectious Diseases
Improvement of prosthetic joint infection diagnosis and treatment
Dr Sheila Patrick
2003-2008
360,142
Infectious Diseases
Molecular pharmacology of cell surface g-protein coupled receptors for Interleukin-8
Dr David Waugh
2003-2009
304,747
Infectious Diseases
Molecular Determinants of Morbillivirus Pathogenesis
Prof Louise Cosby
2004-2009
301,570
Infectious Diseases
Identification and characterisation of Toll-like receptors involved in the response to oral Microbes
Prof James Johnston
2004-2007
302,718
Infectious Diseases
Coxiella burnetii infection in Northern Ireland:  Epidemiology & Diagnosis
Dr Conall McCaughey
2004-2007
447,228
Infectious Diseases
The development, dissemination and significance of antibiotic resistance within the human food chain
Prof David McDowell
2004-2008
547,200
Infectious Diseases
Development and clinical validation of a respiratory microarray to study the clinical significance of concurrent infections of the respiratory tract
Dr Peter Coyle
2005-2008
364,234
Infectious Diseases
Characterisation of in vitro and in vivo rhamnolipid production by opportunistic Pseudomonas aeruginosa isolated from cystic fibrosis patients:  a chemical analysis and functional genomic approach
Dr James Dooley
2005-2009
314,234
Infectious Diseases
A study to compare the efficacy of two potential diagnostic assays:  A Fluorescein conjugated monoclonal antibody in vivo assay and nested real time PCR assay to rapidly and accurately diagnose herpes simplex keratitis
Dr Tara McMullan
2005-2009
205,716
Infectious Diseases
Generation of a genetic signature of severe RSV disease – an important step towards maximising efficiency of Palivizumab (Synagis) prescription
Dr Ultan Power
2007-2012
947,577
Infectious Diseases
Skin bacteria as a source of surgical infections:  molecular Epidemiology and prevention in wound contamination
Dr Sheila Patrick
2008-2015
857,674
Neuroscience & Mental Health
The role of a-synuclein in relation to Parkinson's disease and Dementia with Lewy Bodies
Dr Andrew Wallace
2003-2005
94,413
Neuroscience & Mental Health
Processing of precursor proteins implicated in Alzheimer’s Disease, Parkinson’s Disease, and Dementia with Lewy Bodies
Dr Brent Irvine
2003-2008
533,954
Neuroscience & Mental Health
The role of the prefrontal serotonin system in cognition/Brain SPECT Imaging in Psychiatry
Prof David King 
2002-2008
817,257
Neuroscience & Mental Health
The Genetic Epidemiology of Tardive Dyskinesia in Northern Ireland
Dr Tony O’Neill
2003-2006
275,511
Neuroscience & Mental Health
The Northern Ireland First Episode Psychosis Outcome Study
Dr Teresa Rushe 
2003-2008
835,210
Neuroscience & Mental Health
The application of systematic proteomics to characterise the neuroretina and the inherent subsistence factors that maintain its integrity
Dr Jim Curray
2003-2005
172,627
Neuroscience & Mental Health
Bioinformatic and experimental characterisation of retinal-specific gene expression
Dr David Simpson
2003-2005
245,655
Neuroscience & Mental Health
Determination of platelet BACE activity in Alzheimer’s disease patients and its relationship to genetic variation at the BACE locus
Dr Peter A Passmore
2004-2006
251,832
Neuroscience & Mental Health
A study of motor function and dopamine transporter and receptor status in Parkinson and Parkinson plus syndromes using infra-red oculography, radionucline and MRI imaging
Dr J Mark Gibson
2005-2009
319,883
Neuroscience & Mental Health
The genetic Epidemiology of MS in Northern Ireland
Dr Colin Graham 
2002-2007
403,718
Neuroscience & Mental Health
Individual and family differences in Mental Health:  An Epidemiological Study
Prof Brendan Bunting
2003-2007
1,021,967
Neuroscience & Mental Health
The development and evaluation of a mobile phone-based streaming (MPVS) system in providing home-suport for patients with Alzheimer’s disease
Dr David Craig
2007-2010
262,457